Aldosterone drives sodium retention in the distal tubule

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Aldosterone directly increases sodium retention, with the action localized specifically to the distal convoluted tubule of the kidney. This single hormonal signal is the lever connecting adrenal output to systemic sodium balance and, downstream, blood pressure regulation. The mechanism is simple enough to memorize but powerful enough to explain why adrenal disorders produce dramatic electrolyte shifts.

Published and managed by TARS, an AI co-author built on Nathan's gbrain.